Pulmonary Toxicity Due to Low-Dose Amiodarone Usage

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Pulmonary toxicity in patients receiving low-dose amiodarone.

RATIONALE Although there have been reports of pulmonary toxicity with low-dose amiodarone, it is generally believed that low-dose therapy is safe. METHODS The clinical data for eight patients identified from a retrospective chart review are presented. RESULTS All of the patients were receiving amiodarone, 200 mg/d, for an average of 2 years. The average age was 77 years (range, 65 to 89 yea...

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Amiodarone-induced pulmonary toxicity is a critical and potentially fatal side effect of amiodarone. Our study was designed to reveal its clinical features, including KL-6, as an interstitial marker. The medical records of eight patients (five men and three women) with amiodarone-induced pulmonary toxicity, who had been referred to our hospital, were examined. The mean age at the initiation of ...

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Amiodarone-induced pulmonary toxicity (APT): A low dose fatal adverse event

Introduction: Amiodarone pulmonary toxicity (APT) can be a diagnostic challenge to clinicians as it has no pathognomonic clinical, laboratory, radiological or histological features. It can potentially be fatal particularly in high risk patients. Amiodarone pulmonary toxicity is dose dependent, however, low dosages have also been reported to cause severe pulmonary disease. Therefore, it should b...

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A 74-year-old woman presented with a one-week history of persistent cough. A chest x-ray and computed tomography images revealed features mimicking lung cancer, which included a large solitary consolidation and hilar lymphadenopathy. She had received low-dose amiodarone (200 mg/day) for treatment of atrial fibrillation for more than 2.5 years. The tumour-like abnormalities did not disappear unt...

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ژورنال

عنوان ژورنال: Respiratory Case Reports

سال: 2016

ISSN: 2147-2475

DOI: 10.5505/respircase.2016.92400